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Guidelines For The Diagnosis And Treatment Of Malignant Pleural Mesothelioma Van Zandwijk Journal Of Thoracic Disease Glen Lerner Mesothelioma
Glen lerner mesothelioma. There are four types of mesothelioma defined by tumor location. Malignant pleural mesothelioma mpm is a rare but aggressive and often fatal malignancy most patients present with advanced disease and the median overall survival is approximately 1 y the recommended treatment for mesothelioma is dependent on both stage and histology. Mpm is classified by the world health organization into three major histologic subtypes.
Each histological type of mesothelioma has multiple subtypes which makes each case unique. Compared to other cell types epithelial mesothelioma typically responds better to treatment. Mesothelioma is also identified by three cancer cell types.
For the 3 histologic subtypes of malignant pleural mesothelioma mpm epithelioid sarcomatoid and biphasic the magnitude of benefit with surgical management remains underdefined. Accounting for 50 to 70 percent of all cases epithelial mesothelioma is by far the most common histological subtype. Epithelioid sarcomatoid and biphasic.
Malignant mesothelioma mm has distinct main histological sub types epithelioid sarcomatoid and biphasic it is not known if the type or degree of asbestos exposure can influence the development of different disease sub types exposure variables that were measured in this study were not consistently associated with mm. Epithelioid mixedbiphasic and sarcomatoid galateau salle et al 2016. The national cancer data base was queried for newly diagnosed nonmetastatic mpm with known histology.
According to the 2015 who classification mm is divided into diffuse localized and well differentiated papillary mesothelioma. Furthermore histologic subtype of mm determines the clinical management of the patients. However cell type is not the only factor in a patients prognosis and mesothelioma treatment.
It is therefore the histological subtype associated with the best survival. According to the 2004 world health organization who classification there are three major histologic subtypes of malignant mesothelioma.
Mesothelioma Scientific Clues For Prevention Diagnosis And Therapy Carbone 2019 Ca A Cancer Journal For Clinicians Wiley Online Library Glen Lerner Mesothelioma
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