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Reliability Of P 16 Calretinin And Claudin 4 Immunocytochemistry In Diagnostic Verification Of Effusion Cytology Erin Brockovich Movie True Story
Erin brockovich movie true story. It deals with pericardial fluid peritoneal fluid and pleural fluid. Differentiating reactive mesothelial cells rms from metastatic adenocarcinoma cells mac in serous fluids based on cytomorphologic features alone can be very challenging. Reactive mesothelial cells in the backgrounds of adenocarcinomas were consistently negative for ecadherin.
The wide separation of the nuclei and the well defined nucleoli help to identify these as reactive. Here we analyzed the appearance ratio of intracytoplasmic vacuole cells as it seems to be a useful means to distinguish mesothelioma from reactive mesothelial cells. A total 75 fluid samples containing either reactive mesothelial cells or adenocarcinoma were included in the study.
Various immunocytochemical icc markers have been used to maximize the diagnostic accuracy however cytopathologists still e. Notice in the image on the right how indistinct the cytoplasmic borders are in this clump compared to normal mesothelial cells. To differentiate reactive mesothelial cells and adenocarcinoma cells by using immunocytochemical markers ber ep 4 moc 31 calretinin and hbme 1 in serous effusions.
The article deals with cytopathology specimens from spaces lined with mesothelium ie.
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