Keynote 189, Dissecting The Data With Immune Based Combinations In Advanced Nonsquamous Nsclc Onclive

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Keytruda pembrolizumab in combination with pemetrexed and platinum chemotherapy for the first line treatment of metastatic non squamous nsclc.

Cute unicorn mermaid coloring pages. In keynote 189 first line pembrolizumab plus pemetrexed platinum significantly improved overall survival os and progression free survival pfs compared with placebo plus pemetrexed platinum in patients with metastatic nonsquamous nonsmall cell lung cancer nsclc irrespective of tumor programmed death ligand 1 pd l1 expression. 00001 and pfs hr 052 p 00001 and had manageable safety vs placebo plus pem and platinum as first line therapy for metastatic nonsquamous nsclc. In an exploratory analysis we assessed outcomes by investigators choice of carboplatin carbo or cisplatin cis.

Pembrolizumab or placebo plus pemetrexed and platinum for previously untreated metastatic nonsquamous non small cell lung cancer. Epub 2020 mar 9. In keynote 189 first line pembrolizumab plus pemetrexed platinum significantly improved overall survival os and progression free survival pfs compared with placebo plus pemetrexed platinum in patients with metastatic nonsquamous nonsmall cell lung cancer nsclc irrespective of tumor programmed death ligand 1 pd l1 expression.

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