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Carl mayer john mayer. It contains natural fire and heat resistant qualities making it ideal for building materials. Asbestos is known as mutagenic and carcinogenic for human and is responsible for many pulmonary diseases including asbestosis bronchogenic carcinoma and malignant pleural mesothelioma. Chemical substances are released that cause a slow inflammatory and mutagenic response as.
Combating mesotheliomas resistance to chemotherapy. Mesothelioma cells are good at protecting themselves from chemotherapy. They not only have built in repair mechanisms but they can also develop mutations to prevent further cell damage.
Knowing better about the causes of this disease can help you prevent disease increase awareness and care. The process is called mutagenic translesion synthesis tls. There is growing interest in finding genetic mutations responsible for disease susceptibility.
Asbestos is a natural mineral that was used in a fibrous form in many products throughout the early 20 th century and despite heavy regulation is still used in some products today. Exposure to asbestos is the primary cause of mesothelioma accounting for over 90 of all cases. Indirectly asbestos can cause mesothelial cells to release mutagenic reactive oxygen and nitrogen which also causes mutation.
Tls can make resistance to chemotherapy. Occupational exposure to asbestos is involved in 70 80 of all malignant pleural mesothelioma. The later presents.
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