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Food and drug administration fda has approved a combination of opdivo and yervoy as a first line therapy for adults with inoperable malignant pleural mesothelioma mpm a rare but aggressive cancer that affects the lungs protective tissue lining.

Mesothelioma statute of limitations massachusetts. Opdivo yervoy is approved as a first treatment for adults with malignant pleural mesothelioma that cannot be removed by surgery. Opdivo mesothelioma immunotherapy may be used in combination with surgery chemotherapy or radiation or with two or more of these. Pleural mesothelioma is a hard to treat cancer that grows on the lining around the lungs and causes many of the same symptoms as lung cancer.

Opdivo is a prescription medicine used in combination with yervoy opdivo yervoy to treat a type of cancer called malignant pleural mesothelioma which affects the lining of the lungs and chest wall. It was the first new drug regimen approved for mesothelioma in 16 years and only the second systemic therapy ever. Opdivo and yervoy for recurrent pleural mesothelioma.

The fdas decision was announced less than six weeks after bristol myers squibb the therapies developer submitted an. Dutch study paves the way. Multimodal mesothelioma treatment is the current standard of care for most patients.

If surgery is not possible you may still be able to receive immunotherapy treatment. The study included 38 patients with recurrent pleural mesothelioma and met the primary goal of improving the disease control rate at three months between 20 to more than 40 percent. In the checkmate 743 trial opdivo plus yervoy showed improvements in survival across both.

Researchers around the world are studying opdivo as a single therapy and in combination with other drugs to treat mesothelioma. The news may have implications for people with the lung related asbestos cancer malignant mesothelioma who are also sometimes treated with opdivo. After two years of follow up 41 of patients treated with opdivo plus yervoy combination were alive compared to 27 of patients treated with chemotherapy.

The food and drug administrations fda recent approval of opdivo nivolumab in combination with yervoy ipilimumab for the frontline treatment of adults with unresectable malignant pleural mesothelioma was desperately needed according to dr. In 2015 scientists at the netherlands cancer institute in amsterdam began the first mesothelioma clinical trial for opdivo finding promising results. One recent study dubbed initiate focused on testing the efficacy and safety of immunotherapy drugs nivolumab brand name opdivo and ipilimumab brand name yervoy in pleural mesothelioma patients who had previously been treated with a platinum based chemotherapy drug like cisplatin.

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