Simian Virus 40 Large T Antigen Binds P53 In Human Mesotheliomas, T Antigens Of Simian Virus 40 Molecular Chaperones For Viral Replication And Tumorigenesis Microbiology And Molecular Biology Reviews
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At simian virus 40.
Skeleton coloring pages. We found that simian virus 40 sv40 induces mesotheliomas in hamsters and that 60 of human mesotheliomas contain and express sv40 sequences results now confirmed by others ref. Mew viji shridhar andrea de bartolomeis vincenzo esposito maria teresa giuliano seth m. The large t antigen of simian virus 40 sv40 forms a specific complex with p53 and inhibits p53 mediated transcription.
Here we show that the large t antigens from sv40 and jc virus strongly reduce the transcriptional activity of p53 but do not detectably affect the ability of the p73 proteins to transactivate. Levine antonio giordano harvey i. 3 5 and presentations by d.
A possible human polyoma virus nih workshop 27 28 january 1997 bethesda md transcript available through sag. Nature medicine 3 908912. Simian virus 40 large t antigen binds p53 in human mesotheliomas michele carbone paola rizzo philip m.
P53 but not the p73 proteins. Grimley antonio procopio daphne jy. Carbone m1 rizzo p grimley pm procopio a mew dj shridhar v de bartolomeis a esposito v giuliano mt steinberg sm levine as giordano a pass hi.
The large t antigen of simian virus 40 sv40 forms a specific complex with p53.
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