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What does asbestos cause. Emerging second generation massively parallel dna sequencing technologies have enabled more precise definition of the cancer genome on a global scale. By bueno raphael de rienzo assunta dong lingsheng gordon gavin j hercus colin f richards william g jensen roderick v anwar arif maulik gautam chirieac. Second generation sequencing of the mesothelioma tumor genome.
A map of human genome variation from population scale sequencing. It has an epidemiologically well established causal link with asbestos eg. We examined the genome of a human primary malignant pleural mesothelioma mpm tumor and matched normal tissue by using a combination of sequencing by synthesis and pyrosequencing methodologies.
Second generation sequencing of the mesothelioma tumor genome article pdf available in plos one 55e10612 may 2010 with 148 reads how we measure reads. The 1000 genomes project consortium. Second generation sequencing of the mesothelioma tumor genome raphael bueno12 assunta de rienzo12 lingsheng dong12 gavin j.
Encode phase 3 published. Mesothelioma is a malignant tumour of mesothelium the serosal membrane lining body cavities. Second generation sequencing of the mesothelioma tumor genome.
But with long latency between exposure and clinical presentationworldwide case load of mesothelioma continues to increase due to rising third wave asbestos exposure in some countries and regulatory. We examined the genome of a human primary malignant pleural mesothelioma mpm tumor and matched normal tissue by using a combination of sequencing by synthesis and pyrosequencing methodologies. Emerging second generation massively parallel dna sequencing technologies have enabled more precise definition of the cancer genome on a global scale.
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