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Stoners coloring book. In a study by david a. Palma md and colleagues patients with oligometastatic cancers up to 5 metastatic foci not just lung cancer underwent definitive treatment to their primary cancer and were then randomized to standard of care palliative therapy with or without stereotactic radiotherapy. A systematic review of the literature.
Lacking a precise and consistent definition oligometastatic disease is generally considered to represent a relatively favorable clinical state with more indolent biology a limited number of disease sites and potential for prolonged periods of disease control. The oligometastatic stage iv non small cell lung cancer nsclc offers a new surgical opportunity. Definition of synchronous oligometastatic non small cell lung cancer a consensus report.
Proposals for revision of the tnm stage groupings in the forthcoming eighth edition of the tnm classification for lung cancer. Recent years have seen a markedly increased interest in the concept of oligometastatic disease in nonsmall cell lung cancer nsclc. Is there an oligometastatic state in non small cell lung cancer.
Ashworth ab senan s palma da et al. Lung cancer remains the leading cause of cancer related mortality and non small cell lung cancer nsclc accounts for 80 of all cases. De ruysscher d et al.
New reported data is showing that surgery can offer a reasonable benefit in terms of long term survival to some patients. 197 203 2013 crossref medline google scholar. The advantages of surgical treatment rely on a more adequate patient selectio.
A systematic review of the literature. The iaslc lung cancer staging project. Radical treatment of nonsmall cell lung cancer patients with synchronous oligometastases.
Clin lung cancer 15. This subgroup of patients when receiving ablative therapy such as surgery or stereotactic body radiation radiotherapy can obtain markedly long progression free and overall survival. Long term results of a prospective phase ii trial nct01282450.
Dingemans ac hendriks lel berghmans t et al. Ashworth ab senan s palma da et al. An individual patient data metaanalysis of outcomes and prognostic factors after treatment of oligometastatic non small cell lung cancer.
346 355 2014 crossref medline google scholar. The oligometastatic state is a clinical paradigm whereby cancer patients with limited metastases ie 1 to 5 that are amenable to aggressive management through resection or ablative therapy may survive beyond expectations 1 2at the time of diagnosis non small cell lung cancer nsclc and renal cell carcinoma rcc present with metastatic disease in approximately 56 and 30. An individual patient data metaanalysis of outcomes and prognostic factors after treatment of oligometastatic non small cell lung cancer.
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