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Mesothelioma canada statistics. Based on previous ndings in a variety of other cancers we. Mol ther nucleic acids. Mir 31 has been characterised as a tumour suppressor mirna with its levels varying in breast cancer cells according to the metastatic state of the tumour.
Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma molecular therapy. Hull york medical school hull hu6 7rx uk. Moody h lind m maher s.
Lung cancer 201484271 4. 1school of life sciences university of hull hull hu6 7rx uk. Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma.
Lind 2 3 stephen g. Moody 1 2 michael j. Moody h lind m maher s.
A the hep3b and huh7 cell lines were stably transfected with. Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma. Moody hl1 lind mj2 maher sg3.
Mol ther nucleic acids. Moody hl lind mj maher sg. Based on previous findings in a variety of other cancers we hypothesized that mir 31 alters.
Author links open overlay panel hannah l. Microrna 31 mir 31 is encoded on a genomic fragile site 9p213 which is reportedly lost in many mpm tumors. Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma.
2017 158317 329 additional files. Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma. Microrna 31 mir 31 is encoded on a genomic fragile site 9p213 which is reportedly lost in many mpm tumors.
From its typical abundance in healthy tissue is a moderate decrease in non metastatic breast cancer cell lines and levels are almost completely absent in mouse and human metastatic breast cancer cell lines. Zauderer mg kass sl woo k sima cs ginsberg ms et al. Nucleic acids 2017 september epub 2017 july 8 link moody hl lind mj maher sg asbstract malignant pleural mesothelioma mpm is associated with an extremely poor prognosis and most patients initially are or rapidly become unresponsive to platinum.
Microrna 31 regulates chemosensitivity in malignant pleural mesothelioma. Malignant pleural mesothelioma mpm is associated with an extremely poor prognosis and most patients initially are or rapidly become unresponsive to platinum based chemotherapy. Vinorelbine and gemcitabine as second or third line therapy for malignant pleural mesothelioma.
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