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Mesothelioma stages. Of multiple pulmonary nodules detected with ct scanning 73 are shown to be metastases. Metastatic lung cancer occurs when cancer in another area of the body spreads to the lung. Metastatic pulmonary nodules are usually multiple.
A 40 year old woman was referred to pulmonary clinic for evaluation of multiple lung nodules on chest imaging. Metastatic pulmonary nodules have smooth or irregular margins and are randomly distributed with predilection for the peripheral middle and lower lung zones. Abstract multiple pulmonary nodules are most often metastases from a distant primary tumor but they must be distinguished from a number of inflammatory and infectious diseases that may cause multiple pulmonary nodules or masses.
Pulmonary metastasis may be a single pulmonary mass multiple pulmonary nodules an airspace pattern metastasis a lymphangitic metastasis or an endobronchial metastasis figure 27 21. Another cause of pneumothoraces includes cystic or cavitary pulmonary metastases. A number of differentials must be kept in mind while approaching diffuse or multiple pulmonary nodulesinterpretation is easier if nodules are the only abnormality.
These differentials can be narrowed down based on several criteria. If youve had a chest x ray or other imaging and have been advised that the radiologist spotted multiple lung nodules the first thing that may come to mind is cancerwhen lung nodules occur in isolation solitary pulmonary nodule spn cancer is infrequently the casebut when there are several or many the risk of cancer increases. The differential depends on the number of nodulesmasses and their imaging characteristics.
A single nodule is most common in carcinoma of the colon or kidneys and osteosarcoma. Her past medical history was remarkable for end stage kidney disease on peritoneal dialysis due to chronic hypertension 5 years ago and large uterine leiomyomata that led to total hysterectomy at age 30 years. The metastatic pulmonary nodules or masses can be irregular or circumscribed lesions and tend to be in the periphery of the lung.
Calcification of nodules is common and most often the result of a healed granuloma from tuberculosis or histoplasmosis. Osteosarcoma is classically described as the pulmonary metastasis that results in pneumothorax. Multiple pulmonary nodules mpn is the term used to.
Pathology diagnosis was compatible with multiple uterine corpus and.
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