Mesothelin Mesothelioma, Soluble Mesothelin In Effusions A Useful Tool For The Diagnosis Of Malignant Mesothelioma Thorax
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Blood tests to measure mesothelin help monitor mesothelioma growth and response to treatment.
Tatar kazan people. Lmb 100s first objective is to bind to mesothelin on mesothelioma tumors. Mesothelioma is a highly aggressive tumour for which there are no reliable serum tumour markers. Increased pleural fluid mesothelin is suggestive of mesothelioma or metastatic carcinoma especially ovarian or pancreatic adenocarcinoma and helps determine if thoracoscopy is required.
The antigen is produced at higher levels when the cells turn cancerous. Mesothelin is a protein made by mesothelial cells that line the pleura peritoneum and pericardium. However mesothelioma is a stubborn fast spreading cancer.
The drug then delivers a toxin into the diseased cells which eventually undergo cell death.
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