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Denver adding the antiangiogenic antibody bevacizumab to chemotherapy improves outcomes in patients who have unresectable mesothelioma with little downside according to results of maps the mesothelioma avastin plus pemetrexed cisplatin study.

Mesothelioma case study. Mesothelioma avastin plus pemetrexed cisplatin study maps the safety and scientific validity of this study is the responsibility of the study sponsor and investigators. The maps 2 study which examined bristol myers squibbs opdivo withwithout yervoy in second or third line patients showed an impressive set. Epub 2015 dec 21.

A randomised controlled open label phase 3 trial lancet. In 2015 we initiated a phase 3 open label randomised controlled trial the ifct gfpc 0701 mesothelioma avastin plus pemetrexed cisplatin study maps which showed an overall survival benefit when adding bevacizumab to standard cisplatin plus pemetrexed chemotherapy median overall survival 188 months 95 ci 159226 with bevacizumab. Listing a study does not mean it has been evaluated by the us.

Bevacizumab for newly diagnosed pleural mesothelioma in the mesothelioma avastin cisplatin pemetrexed study maps. Median overall survival in the multicenter randomized phase iii trial was 275 months longer for patients given bevacizumab in addition to the. The phase 23 mesothelioma avastin cisplatin pemetrexed study maps was initiated to assess the effect on survival of bevacizumab when added to the present standard of care cisplatin plus pemetrexed as first line treatment of advanced malignant pleural mesothelioma.

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