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Cancer causing pleural effusion. Recurrences were evaluated according to known prognostic factors and whether malignant cells were present in peritoneal cytologic specimens. Immunostaining using cell block material is useful to help differentiate malignant cells from reactive mesothelial cells. Peritoneal washings or brushings are usually obtained in circumstances where the primary abdominal or pelvic lesion has been identified and the main concern is about diagnosis of malignancy.
Mpm accounts for 20 to 30 of all cases of mesothelioma. Cytologic examination of peritoneal fluid aids in staging ovarian malignancies and in selecting gastric adenocarcinoma patients for intraoperative adjuvant chemotherapy. Laparotomy 5 patients and laparoscopy 7 cases were diagnostic in all cases.
However when malignant cells are present in peritoneal fluid this tends to neutralize the good prognostic factors and cytologic findings become a predominantly important consideration. Mesothelial cells during injuries or infection. Thrombocytosis was present in 11 cases.
Peritoneal mesothelioma develops in the lining of the abdominal cavity called the peritoneum. Peritoneal fluid cytology was positive for neoplastic mesothelial cells in 8 of 10 cases. Cases of mesothelioma have.
If malignant cells are not present in peritoneal cytologic specimens the influence of known prognostic factors remains intact. The role of cytologic evaluation of pleural fluid in the diagnosis of malignant mesothelioma. Diagnosis in vita was malignant peritoneal mesothelioma for 13 patients peritoneal carcinomatosis for 1 with only 1 autopsy diagnosis.
Pericardial mesothelioma originates in the pericardium which lines the heart. Tissue culture of peritoneal fluid could be potentially valuable in confirming cell viability and establishing sensitivity to a variety of anti cancer agents. Malignant peritoneal mesothelioma mpm is a rare insidi ous and aggressive neoplasm that arises from the mesothelial lining of the peritoneum.
Tsujimura t kawai t et al.
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