Wt1 Negative Mesothelioma, Pathology Outlines Diffuse Malignant Mesothelioma
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Role Of P16 Deletion And Bap1 Loss In The Diagnosis Of Malignant Mesothelioma Liu Journal Of Thoracic Disease Sokoloff Law
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Stains molecular markers wt1.
Sokoloff law. Wt1 mutation in malignant mesothelioma and wt1 immunoreactivity in relation to p53 and growth factor receptor expression cell type transition and prognosis j pathol 1811. But the specificity of these markers for the differentiation of sarcomatoid mesothelioma and sarcomatoid carcinoma is relatively low. It appears that wt1 is a positive marker while ema is a negative marker for sarcomatoid mesothelioma.
The international mesothelioma interest group imig identifies wt1 as one of the most useful markers for mesothelioma diagnosis. After analyzing the results it is concluded that calretinin cytokeratin 56 and wt1 are the best positive markers for differentiating epithelioid malignant mesothelioma from pulmonary adenocarcinoma. Therefore these markers are not useful for differentiating these tumors.
Hbme 1 moc 31 wt1 and calretinin. Acute myeloid leukemia cystic partially differentiated nephroblastoma desmoplastic small round cell tumor malignant mesothelioma metanephric adenoma nephrogenic rests ovarian carcinomas serous carcinoma almost all transitional small cell am j surg pathol 2005291034 peritoneal serous carcinoma involving an endometrial polyp 80 am j surg pathol. Wt1 as an immunohistochemical marker for mesothelioma.
An assessment of recently described markers for mesothelioma and adenocarcinoma. Useful to distinguish mesothelioma from renal cell carcinoma and squamous cell carcinoma hum pathol 2013441 negative stains ttf1 and napsin a.
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