Southampton Mesothelioma Trial, Wish Lab Southampton On Twitter Confirm Immunotherapy Phase Iii Trial Looking At Nivolumab Anti Pd1 Receptor In Relapsed Mesothelioma Poster Uos Medicine Faculty Conference Today Southamptonctu Cruksouthampton Rdsouthampton Https T Co

Please note unless we state otherwise in the summary you need to talk to your doctor about joining a trial.

Unicorn cake coloring pages free. A double blind placebo controlled phase iii clinical trial investigating the effect of nivolumab in patients with relapsed mesothelioma. Age 18 and above 6. May 19 2017 source.

Anyone wanting more information about the trial should contact their consultant or the southampton clinical trials unit on 02381 205154 or ctuatsotonacuk. New trial to fight cancer caused by asbestos date. A phase 3 british clinical trial will test whether the immune checkpoint inhibitor opdivo nivolumab can help mesothelioma patients whose disease relapsed after platinum based chemotherapy.

A phase iii trial to evaluate the efficacy of nivolumab in relapsed mesothelioma. Mesothelioma will be the first ever placebo controlled randomised phase iii pd1 immunotherapy trial for relapsed mesothelioma. Inhibition of focal adhesion kinase has been shown to selectively kill mesothelioma cells that express low levels of moesin ezrin radixin like protein merlin.

Study protocol for a randomised controlled trial. Ecog performance status 0 1 4. Evidence of disease progression which is radiologically assessable through recist on ct scan within 28 days of trial treatment 5.

Patients with a hard to treat type of cancer are being given new hope in a. 1313 university of chicago medical center chicago il. 1414 erasmus medical college rotterdam the netherlands.

University of southampton summary. Please go to the find a clinical trial search page to search for other trials. The confirm trial nct03063450 funded by cancer research uk has begun enrolling patientsthe goal is to have 304 participants at 20 sites in london southampton leicester and other cities.

The mesothelioma stratified therapy mist trial is a british lung foundation funded university of leicester study a multi arm stratified therapy based clinical trial for patients with relapsed mesothelioma. Prior treatment with at least two lines of platinum based chemotherapy 3. Histological confirmation of mesothelioma 2.

1212 university hospital southampton united kingdom. Confirm is a double blind randomised phase iii trial comparing nivolumab anti pd 1 antibody monotherapy versus placebo in patients with mesothelioma. The trial which is being run in collaboration with the clinical lead professor dean fennell at the university of leicester plans to recruit 336 patients who have relapsed mesothelioma across 20 uk wide sites including southampton and leicester.

Screening laboratory values within protocol specified ranges 7.