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Pesticides mesothelioma. The name synovial sarcoma was coined early in the 20th century as some researchers thought that the microscopic similarity of some tumors to synovium and. Synovial sarcoma is a rare and aggressive soft tissue sarcoma. This is a critical distinction because synovial sarcoma may be extremely aggressive.
The incidence of pleural synovial sarcoma has been shown to be increasing and the most common therapy is a surgical resection 67 followed by chemotherapy. Because of its rarity pleural synovial sarcoma is often mistaken for the histologically similar malignant mesothelioma the most common of the pleural neoplasms. The diagnosis is made after excluding metastasis from an extrathoracic sarcoma.
We report a case of a 67yearold gentleman who presented with an incidental finding of a left lung mass on a routine chest xray. In fact pleural synovial sarcoma was first described only 6 years ago 7 and has not yet been reported in the surgical literature. However as the tumor grows larger affected people may notice a lump or swelling.
Primary pleural synovial sarcoma ppss is an extremely rare malignancy without a known cause. In general synovial sarcomas are chemosensitive to ifosfamide and doxorubicin but there is no established gold standard for the treatment of pleural synovial sarcoma. In the early stages of the condition it may cause no noticeable signs or symptoms.
It together with primary synovial sarcoma of the lung comes under the broader category of pleuro pulmonary synovial sarcomas. It is a type of soft tissue sarcoma. Studies in the last 10 years have shown it to be extremely sensitive to ifosfamide based.
6 pleural synovial sarcoma however is a much rarer entity. It may originate in the pulmonary parenchyma tracheobronchial tree pleura chest wall mediastinum or pulmonary artery. Pulmonary sarcomas constitute only 0105 of all primary lung malignancies.
The most frequently reported subtypes of sarcomas in the lung are leiomyosarcoma malignant fibrous histiocytoma fibrosarcoma and more recently synovial sarcoma 1the term synovial sarcoma first appeared in the german surgical literature in 1865 where it was used to describe a complex multi. In some cases the tumor can limit range of motion or cause numbness andor pain if it presses on nearby nerves. Synovial sarcoma is a soft tissue malignant tumour and the majority of that occur in extremities.
A synovial sarcoma also known as. Primary pulmonary synovial sarcoma ppss is a rare malignancy that represents less than 05 of malignant pulmonary neoplasms and 10 of primary pulmonary sarcomas.
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