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Cytomorphological Profile Of Neoplastic Effusions An Audit Of 10 Years With Emphasis On Uncommonly Encountered Malignancies Gupta S Sodhani P Jain S J Can Res Ther Mesothelioma Testicular
Mesothelioma testicular. Pleural effusion is a relatively common finding in patients with non hodgkin lymphoma nhl with a frequency of up to 20. 1 pleural infiltration by the lymphoma with shedding of cells into the pleural space 2 lymphatic obstruction by lymphomatous infiltration of pulmonary and mediastinal lymph nodes. Pleural effusion is a common finding in patients with non hodgkin lymphoma with a reported incidence of 16 to 20.
However transudative effusion can occur from heart failure or venous compression. Pels grow mainly in the body cavities pleural pericardial and peritoneal as lymphomatous effusions without an identifiable contiguous tumor mass. Primary effusion lymphoma pel or body cavityassociated lymphoma is a rare type of non hodgkin lymphoma that occurs almost exclusively with hiv 1 infection.
Presence of pleural effusion in lymphoma is considered a poor prognostic indicator 2. It invariably is an exudate but occasionally can be chylous. The presence of pleural effusion at the time of presentation is not only associated with extremely poor outcome of lymphomas it is also a predictor of disease relapse after chemotherapy and decreased survival.
Systemic chemotherapy talc pleurodesis and radiation therapy can be considered as treatment options 4. The ct scan identified biopsy sites when pleural fluid and tissue studies were nondiagnostic. Among them 60 account for dlbc lymphoma.
Primary effusion lymphoma pel is classified as a diffuse large b cell lymphoma. 1 in addition up to 10 of malignant pleural effusions with a positive cytologic examination are due to nhl. Serous effusions are a common complication of lymphomas.
Although the frequency of pleural effusion in 20 30 in non hodgkin lymphoma and hodgkin disease the involvement of peritoneal and pericardial cavities is uncommon. Pleural involvement with lymphoma can occur in two situations. 1 pleural effusion may develop in nhl patients by three different mechanisms.
And 3 obstruction of the thoracic duct which results in chylothorax. It is a rare malignancy of plasmablastic cells that occurs in individuals that are infected with the kaposis sarcoma associated herpesvirus ie. 1 4 thoracentesis results in a positive cytologic diagnosis in 6090 of patients with nhl.
Pleural effusions are more commonly seen than pleural thickening or pleural masses 45.
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