Pemetrexed Mesothelioma, Mco 2011 Slide 29 R A Stahel Mesothelioma

Or any other drugs foods or substances.

Pinkie pie equestria girl coloring page. Pemetrexed is the generic name for the chemotherapy drug alimta which is administered intravenously. The introduction of pemetrexed alimta eli lilly a multitargeted antifolate agent has improved the outlook for patients with mesothelioma by demonstrating a positive impact on quality of life and by prolonging survival. Alimta is a chemotherapy drug specifically approved for treatment of mesothelioma.

It may be given to you for other reasons. Pemetrexed in malignant pleural mesothelioma. Talk with the doctor.

Food and drug administration fda of a new drug application for the treatment of malignant pleural mesothelioma mpm. The injection version of pemetrexed is branded pemfexy. Food and drug administration fda approved alimta for first line treatment in patients with mesothelioma who are not candidates for curative surgery.

Pemetrexed may also be a radiosensitizer 20. Patients with malignant pleural mesothelioma a rapidly progressing malignancy with a median survival time of 6 to 9 months have previously responded poorly to chemotherapy. Malignant pleural mesothelioma mpm is a disease with a poorprognosis related in part to the aggressiveness of this disease and inpart due to the lack of drugs that have demonstrated tumor activityhistorically antifolates such as.

This report describes the data and analysis leading to the approval of pemetrexed ly 231514 mta alimta eli lilly and co indianapolis in by the us. Alimta also known generically as pemetrexed is a chemotherapy drug developed and marketed by eli lilly and company for cancer treatment including for patients with malignant pleural mesothelioma and nonsquamous non small cell lung cancer nsclc. It is the most effective chemotherapy drug for mesothelioma.

The fda review of the efficacy and safety of pemetrexed assessed in a randomized clinical. Any part of pemetrexed. Alimta manufactured by the pharmaceutical company eli lilly is the trade name for the generic drug pemetrexed.

Pemetrexed is one of two fda approved chemotherapy drugs for mesothelioma. Pemetrexed also has the effect of synchronization of the cell cycle and the resulting accumulation of tumor cells in the s phase has the potential to sensitize cells to the cytotoxic effects of other agents particularly gemcitabine 1819. Pemetrexed is marketed by eli lilly and company under the brand name alimta.

If you have an allergy to pemetrexed or any other part of pemetrexed. What do i need to tell my doctor before i take pemetrexed. The other is cisplatin.

It is used to treat mesothelioma. We conducted a phase iii trial to determine whether treatment with pemetrexed and cisplatin results in survival time superior to that achieved with cisplatin alone. Doctors often combine alimta with platinum based drugs such as cisplatin and carboplatin to increase its effectiveness.