Nkx3 1 Mesothelioma, Malignant Tumors In Hernia Sac Clinicopathological And Immunohistochemical Studies Of 21 Cases At A Single Institution Zhang Pathology International Wiley Online Library

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Malignant mesothelioma of the tunica vaginalis testis also known as paratesticular mesothelioma is a rare tumour comprising less than 1 of all mesotheliomas 1 2since the first record in 1957 only case reports and case series have been published with less than 300 patients worldwide to date 3 4the majority of these cases presented as an incidental finding during hydrocelectomy 4 5.

Secret life of pets coloring pages free. Prostein is a transmembrane protein with a high specificity for benign and malignant prostatic epithelium. Malignant mesothelioma is an aggressive neoplasm of the serosal lining of the chest etiologically linked to asbestos. Nkx31 is a nuclear marker that more frequently stains high grade carcinoma than psa.

Given the unusual morphology and nonspecific staining pattern the case was signed out as a poorly differentiated malignant neoplasm pending further characterization with additional stains. Ttf 1 napsin a p40 and nkx31 were negative. It may also be expressed in some other tissues such as testicular germ cells and lobular carcinoma of breast.

Calretinin can be demonstrated in both benign mesothelium and in malignant mesothelioma and can be used to help differentiate mesothelioma from adenocarcinoma especially useful in lung tumours. Antibodies to calretinin can also be used to distinguish between different types of brain tumour demonstrating only those with neuronal rather than. Positive in some psa neg poorly differentiated adenocarcinomas.

Nkx31 prostate adenocarcinomas high specificity and sensitivity.

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