Mesothelioma Synthetic Vitreous Fibers, 2
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Two population based case control studies 1979 1986 and 1996 2001 provided 35 histologically confirmed mesothelioma cases and 1965 controls.
Lawrence levy. Thin asbestos fibers that are dispersed into workroom or ambient air are readily inhaled and have caused lung and pleural fibrosis lung cancer and mesothelioma. Synthetic vitreous fibres svfalso known as man made mineral fibres mmmf synthetic mineral fibres smf and man made vitreous fibres mmvfhave been used extensively in the construction industry as insulating and fire protection material. Systematic reviews of synthetic vitreous fibers have concluded that the combined evidence based on epidemiologic and toxicologic data provides little support of any increased risk of mesothelioma following exposure.
To examine the effects of exposure to occupational asbestos and man made vitreous fibers mmvf across a wide range of occupations on risk of mesothelioma. Objective we investigated whether available epidemiological and toxicological data suggest an increased risk of mesothelioma among workers exposed to synthetic vitreous fibers svf. Methods we conducted a systematic review of epidemiological studies on the risk of mesothelioma among workers exposed to svf and toxicological studies on svf and mesothelioma.
The most widely used substitutes for thin asbestos fibers include synthetic vitreous fibers such as rock wool and slag wool. Asbestos and manmade vitreous fibers as risk factors for diffuse malignant mesothelioma. These fibers differ from natural mineral fibers such as asbestos because they do not have a crystalline molecular structure.
Mandel a systematic review of occupational exposure to synthetic vitreous fibers and mesothelioma critical reviews in toxicology 103109104084442014899558 44 5 436 449. Results from a german hospitalbased casecontrol study.
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