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Chrysotile asbestos mesothelioma and garage mechanics. Morphologically psammoma bodies are more common in ovarian cancer than mesothelioma. Examination of papillary architecture nuclear atypia and mitotic rates can further aid in distinguishing these two entities. Psammoma bodies heres a good mnemonic to figure out which cancers have psammoma bodies concentric laminated calcified spheres.
They have a lamellated concentric calcified structure sometimes large enough to be seen on ct. Papillary thyroid renal serous ovary meningioma mesothelioma. Psammoma bodies are round microscopic calcific collections.
Psammoma bodies are concentrically laminated calcifications seen in malignant tumors that have papillary architecture like primary pulmonary adenocarcinoma mesothelioma metastatic thyroid or ovarian cancer. Keratin pearl a term for a round laminated 20100 um diameter calcified mass seen by light microscopy which corresponds to degenerated papillary clusters of cellular debris. In serous ovarian cancers the papillae have more hierarchical branching.
Papillary carcinoma of the thyroid and if you want more detail papillary renal cell carcinoma prolactinoma. A psammoma body has actual calcium in it which stains blue and looks crunchy. A review of 35 cases with diagnosis and prognosis.
Psammoma bodies appear in benign and malignant conditions. Related to psammoma body. A keratin pearl just has keratin in it which stains pink and often looks just like the keratin on top of keratinized epithelium.
It is a form of dystrophic calcificationnecrotic cells form the focus for surrounding calcific deposition. Calcification of intralymphatic tumor thrombi. Psammoma bodies are commonly seen in certain tumors such as.
They are often associated with a papillary architecture. Psammoma bodies are found in a diverse group of tumors which include. Psammoma bodies are associated with the papillary nipple like histo morphology and are thought to arise from.
Serous cystadenocarcinoma of the ovary.
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