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Free online color by number games. The most common area affected is the lining of the lungs and chest wall. Like all cancers mesothelioma is literally a genetic disease. Research bolsters idea of other genetic risk factors.
Less commonly the lining of the abdomen and rarely the sac surrounding the heart or the sac surrounding the testis may be affected. Signs and symptoms of mesothelioma may. Unlocking the connection between genetic risk factors of mesothelioma helps researchers develop prevention techniques and more effective treatment options.
The genetic components of malignant mesothelioma are not well understood. Asbestos is the most important risk factor and cause of this cancer but individual genetics likely also play a role. People without a genetic predisposition to a disease can still develop the disease but the risk is much lower.
In this case the daughters disease was even more aggressive than her fathers. Mesothelioma is a type of cancer that develops from the thin layer of tissue that covers many of the internal organs known as the mesothelium. But the disease clusters in families that do not have bap1 mutations suggesting other genes play a role in mesothelioma risk.
Mesothelioma experts know of mutations in only one gene bap1 that are strongly associated with increased risk of mesothelioma. Asbestos is the most important risk factor and cause of this cancer but individual genetics likely also play a role. Mesothelioma occurs when the genes of normal healthy cells mutate and transform into mesothelioma cells.
Specific genes that have been linked to predisposition andor progression of mesothelioma include the tumor suppressor genes bap1 cdkn2a and nf2. It isnt clear what causes the initial genetic mutations that lead to mesothelioma though researchers have identified factors that may increase the risk. The most well known mesothelioma genetic risk factor is bap1 a tumor suppressor gene.
Cancer researchers are identifying the specific genes that cause or result from mesothelioma to use this information to diagnose patients.
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