Mesothelioma Genetic Risk Factors, 5tdzcdee3tcykm

But having a known risk factor or even many does not mean that you will get the disease.

Coffee cup coffee coloring pages. Mesothelioma experts know of mutations in only one gene bap1 that are strongly associated with increased risk of mesothelioma. Its likely that cancers form because of an interaction between many factors such as inherited conditions your environment your health conditions and your lifestyle choices. Risk factors for mesothelioma are numerous but the leading factor is asbestos exposure.

Medical researchers have documented a rare genetic mutation called bap1 that increases mesothelioma risk. Researchers have found some factors that increase a persons risk of mesothelioma. Unlocking the connection between genetic risk factors of mesothelioma helps researchers develop prevention techniques and more effective treatment options.

As with other cancers some families appear to be genetically predisposed toward developing the condition meaning exposure to asbestos like fibrous minerals leads to a higher rate of development of mesothelioma among these individuals. Research bolsters idea of other genetic risk factors. However there are other factors and pre existing conditions that could increase risk.

Genetic causes of mesothelioma. Several studies show mutations of bap1 increase the risk of developing mesothelioma. No association was found between spousesfamily history of mesothelioma including both parental and sibling history is an important risk factor for mesothelioma.

The most well known mesothelioma genetic risk factor is bap1 a tumor suppressor gene. It isnt clear what causes the initial genetic mutations that lead to mesothelioma though researchers have identified factors that may increase the risk. A 2018 study published in the journal familial cancer found another potential genetic link to the disease.

Genetics an unclear risk factor in mesothelioma is the role of genetics. In addition genetic testing can be used to distinguish mesothelioma. Asbestos exposure is the only proven cause of mesothelioma.

Others like a persons age or family history cant be changed. Older men who worked in industries with asbestos have the highest risk of receiving a mesothelioma diagnosis. Other factors that may contribute to the development of this cancer is exposure to other minerals and genetic factors.

But the disease clusters in families that do not have bap1 mutations suggesting other genes play a role in mesothelioma risk. Shared genetic factors may contribute to the observed familial clustering of mesothelioma but the contribution of shared environmental factors could not be neglected. When inhaled or ingested the fibers may become lodged within the lining of the internal organs leading to cancer.