Mesothelioma Ema Desmin, Http Handouts Uscap Org 2016 Cm06 Daci 1 Pdf

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Glut 1 ema and desmin expression were evaluated by immunocytochemistry on cbs. To our knowledge this case of peritoneal mesothelioma is the first to describe an opposite immunohistochemical profile to that expected being ema negative and desmin positive despite macroscopic and microscopy evidence of malignancy. The combination of positive ema and negative desmin strongly favors mm.

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Calretinin wt1 pancytokeratin ae1ae3 cam52 epithelial membrane antigen ema desmin asmooth muscle actin asma s100 protein s100p cd34 and cd68.

Xmas pictures to colour in free. 8 13 19 in mesothelioma cells ema staining is mainly seen on the cell surfaces but in carcinoma cells ema stains the. Ema is a high molecular weight transmembranous glycosylated protein of the breast mucin complex which is useful for epithelial differentiation and has been found to be present on both carcinoma and mesothelioma cells. The primary antibodies used in the present study are as follows.

The grade of positivity was. However immunostains such as glut 1 p53 desmin ema imp3 and ezh2 in our opinion have an insufficient specificity and therefore are not useful for the distinction between malignant and reactive mesothelial proliferations. Dilution and incubation periods of these markers are shown in table 2.

Logistic regression lr analysis was applied to a combination of glut 1 and ema. Conversely a combination of negative ema and positive desmin favors a reactive process. Each antibody was compared using roc values where the area under the curve auc was 090 082 and 084 for glut 1 ema and desmin respectively.

Likewise strong membranous positivity for glut 1 andor strong nuclear staining for p53 favors a mesothelioma. Ki67 proliferative index sh.

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Mesothelioma Ema Desmin, Http Handouts Uscap Org 2016 Cm06 Daci 1 Pdf

Calretinin wt1 pancytokeratin ae1ae3 cam52 epithelial membrane antigen ema desmin asmooth muscle actin asma s100 protein s100p cd34 and cd68.

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