Mesothelial Cells With Reactive Changes, Fluid Cytology In Serous Cavity Effusions

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The lesion consists of focal to multifocal and sometimes diffuse hyperplasia and hypertrophy of mesothelial cells figure 2324mesothelial hyperplasia is often accompanied by pleural fibrosis figure 2324.

Rapunzel coloring pages pdf. Reactive mesothelial cells tend to come in clusters and clumps and have a more washed out cytoplasm in body fluids. Notice in the image on the right how indistinct the cytoplasmic borders are in this clump compared to normal mesothelial cells. Pleural mesothelial hyperplasia is typically a secondary change associated with a variety of lung diseases including infection inflammation thoracic effusions and pulmonary neoplasms.

Cytologic atypia in mesothelial cells from peritoneal washings may be due to reactive changes associated with cyst or adnexal torsion visceral adhesions organizing hematoma and inflammatory lesions such as pancreatitis and chronic salpingitis. Reactive mesothelial cells are also present together with the metastatic neoplastic lesion on the mesothelial surfaces. The borderline between reactive changes and the highly differentiated mesothelioma is the best known example of these difficulties.

15 intraperitoneal chemotherapy may give rise to cytologic abnormalities that mimic malignancy.

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