Mars 2 Trial Mesothelioma Protocol, Https Www Zora Uzh Ch 146525 1 Atm 05 11 237 Pdf
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The value of extrapleural pneumonectomy epp in the context of multimodality therapy for patients with malignant pleural mesothelioma is controversial.
Will a ct scan show mesothelioma. Mesothelioma and radical surgery 2 mars 2. You would have this chemotherapy whether you took part in this trial or not. The mars2 trial assessed the role of lung sparing surgery and chemotherapy compared to chemotherapy alone for the treatment of malignant pleural mesothelioma.
The study will test the hypothesis that surgery and chemotherapy is superior to chemotherapy alone with respect to overall. You have these drugs through a drip into a vein once every 3 weeks. Each 3 week period is called a cycle of treatment and you have 2 cycles.
Several phase 2 studies have been reported on the role of neoadjuvant chemotherapy epp and postoperative radiotherapy. The pilot study was funded by cancer research uk and mesothelioma uk has contributed towards patient travel expenses. The purpose of the qas was to.
Warnock c lord k taylor b tod a. This study was designed and delivered in collaboration with the bristol trials centre clinical trials and evaluation unit cteu a uk clinical research collaboration ukcrc registered clinical trials unit which as part of the. Patient experiences of participation in a radical thoracic surgical trial.
The mars mesothelioma and radical surgery trial is open and recruiting in britain. The christie research publications repository. Findings from the mesothelioma and radical surgery trial 2 mars 2.
If the trial proves feasible we will seek to make an international study. Protocol for a multicentre randomised trial comparing extended pleurectomy decortication versus no extended pleurectomy decortication for patients with malignant pleural mesothelioma eric lim1 liz darlison23 john edwards4 daisy elliott5 d a fennell6. Malignant pleural mesothelioma extrapleural pneumonectomy randomized controlled trial trimodality cancer treatment.
This is a phase 3 trialthe researchers need 328 people to join. Mars 2 10 april 2019 protocol version 60 page 6 of 33 the uk mesothelioma research community is the only research group in the world to have recruited over 246 patients and completed and published two randomised trials of surgery for mesothelioma mars 1 and mesovats and the work has influenced mesothelioma practice worldwide. First of all everyone taking part has chemotherapy for mesotheliomayour doctor will decide which drugs you have.
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