Malignant Epithelioid Mesothelioma Of The Lymphohistocytoid Variant, Ijms Free Full Text Inherited Genetic Mutations And Polymorphisms In Malignant Mesothelioma A Comprehensive Review Html
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The lymphohistiocytoid variant of diffuse malignant mesothelioma is rare with very few cases described in the literature.
Find me an attorney. It has been related to asbestos exposure. Prognosis was similar to that of a large series of epithelioid diffuse malignant mesotheliomas. We studied clinicopathologic features and immunohistochemical patterns of a series of 22 cases.
The prominent lymphoid component showed a cytotoxic t cell immunophenotype. Malignant lymphohistiocytoid mesothelioma is a very rare histological variant of malignant sarcomatoid mesothelioma. Lymphohistiocytoid malignant mesothelioma is an infrequent variant of sarcomatoid mesothelioma representing approximately 05 33 of malignant mesotheliomas.
It is characterized by mesothelial cells with a histiocytelike appearance and an associated dense lymphoid infiltrate. Formely it was classified within the sarcomatoid type. The histiocytelike cells had a mesothelial immunophenotype.
This is a rare subtype constituting less than 1 of all of malignant mesotheliomas 3it has traditionally been classified with sarcomatoid mesothelioma but its prognosis is more in keeping with the usual epithelioid mesothelioma.
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