Longo Mallette Mesothelioma, Meothelioma

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Fibroblasts derived from elderly individuals that are still proliferating exhibit a pro inflammatory signature that upon faulty chromosome segregation evolves into a full blown senescent state permanent cell cycle arrest macedo et al 2018 fig. The presence of asbestos in talc would cause the talc to be viewed as a human carcinogen. Qpcr of p16 ink4a p21 waf1cip1 and sasp factors including il6 il8 groalphacxcl1 igfbp2 and il1beta.

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