Keytruda Mesothelioma Europe, Durvalumab With First Line Chemotherapy In Previously Untreated Malignant Pleural Mesothelioma Dream A Multicentre Single Arm Phase 2 Trial With A Safety Run In The Lancet Oncology

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Mesothelioma is a rare but fatal form of thoracic cancer that is diagnosed in more than 30000 people per year and kills over 25000.

Steampunk colouring pages. The randomized trial compared two different treatments involving pembrolizumab or keytruda with standard chemotherapy for patients with progressive malignant pleural mesothelioma. A multicenter randomized phase iii trial comparing pembrolizumab versus standard chemotherapy for advanced pre treated malignant pleural mesothelioma mpm results from the european thoracic. V similarly in october 2016 the food and drug administration in the us approved keytruda as a first line treatment for non small cell lung cancer.

Keytruda is already approved for the treatment of several types of cancer in europe. Cancer is a devastating disease and in europe lung cancer is one of the most deadly forms of the disease. The european society of medical oncology esmo conference last month included results from the phase 3 promise pleural mesothelioma clinical trial.

The disappointing results from the promise meso study were presented at the european society of medical oncology esmo annual meeting last week. Researchers at the european thoracic oncology platform etop didnt get the results they hoped for after a recently completed phase 3 trial for mesothelioma treatment. There has been another win for one of the most promising new drugs for mesothelioma the immunotherapy drug keytruda pembrolizumab.

Melanoma that has spread or cannot be removed with surgery. In europe the european medicines agency ema approved the use of keytruda in melanoma and non small cell lung cancer where the patient had been treated with at least one chemotherapy regime. A novel clinical trial aiming to train the immune system to recognize and attack pleural mesothelioma tumor cells has opened with considerable optimism across five european countries.

The randomized phase iiiii study is designed to measure the efficacy and anti tumor activity of mesopher a vaccine combining a patients own dendritic immune cells with a specially engineered cell line. Keytruda did not improve progression free survival for mesothelioma patients who progressed after first line chemotherapy. The makers of keytruda today announced that when combined with the mesothelioma drug alimta pemetrexed and the platinum based drug cisplatin it significantly extended the survival of lung cancer patients.

Keytruda is an immunotherapy cancer drug which has shown promise in clinical trials for extending life expectancy in mesothelioma patients.

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