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Gospel coloring pages. Few 6 received induction chemo therapy. Inclusion criteria for this investigation were patients with newly diagnosed nonmetastatic and node positive mpm. As all patient information in the ncdb is de identified this study was exempt from institutional review board evaluation.
Of these 14090 underwent definitive treatment and only 508 36 received definitive rt. There is no standard of care with respect to the use of neoadjuvant chemotherapy nac in resectable malignant pleural mesothelioma mpm. The ncdb is a joint project of the commission on cancer coc of the american college of surgeons and the american.
The ncdb participant user file corresponding to mesothelioma 20042013 was utilized for this study. These paradigms are being compared in an accruing randomized phase ii trial. There are 2 main treatment paradigms recognized by the national comprehensive cancer network for resectable malignant pleural mesothelioma mpm.
A minority n116 5 of patients received resection without chemotherapy although this comprised over. Induction chemotherapy followed by resection icr and up front resection with postoperative chemotherapy rpc. We performed an intention to treat analysis with data from a single institution and the national cancer database ncdb to identify whether the use of nac impacts survival in resectable mpm.
25 50 of malignant pleural mesothelioma mpm cases and. Ohri and colleagues reviewed 23414 patients who were entered in the ncdb database between 2004 and 2013. Comprehensive cancer network for resectable malignant pleural mesothelioma mpm.
The ncdb participant user file corresponding to mesothelioma 2004 2012wasusedforthisstudy. These paradigms are being. As a retrospective cohort analysis it is limited by selection bias that cannot be entirely adjusted for.
We do not know the reasons driving receipt of induction therapy in the ncdb.
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