Fibres In Lungs, The Asbestos Fibre Burden In Human Lungs New Insights Into The Chrysotile Debate European Respiratory Society

In each of these twoseries of experiments.

Histological types of mesothelioma. Since cellulose fibres were found in the lungs of our patient and a foreign body tissue reaction to cellulose was confirmed it was concluded that he suffered from a condition that could be called cotton dust pneumoconiosis. Ciliated epithelium consists of cells with cilia. Some inhaled asbestos fibers reach the lungs where they become lodged in lung tissue especially at bifurcations and in the lower lung fields.

Elastic fibers are found in the skin lungs arteries veins connective tissue proper elastic cartilage periodontal ligament fetal tissue and other structures. Elastic fibers stain well with aldehyde fuchsin orcein and weigerts. The half lives of asbestos fibers vary but some are retained in the lungs for many years.

The tiny particles of fiberglass dust in lungs are expelled out rapidly from the alveoli after they are inhaled. Examination of histopathology slides of lung tissue with polarized light confirmed the presence of inhaled cellulosic and plastic fibers. It is well known that chrysotile fibre numbers in the human lungs are lower than amphibole fibre numbers 811 although chrysotile was more frequently used in industry.

Finally the inner lining of the trachea and bronchi is a layer of ciliated epithelium containing goblet cells. This may be explained by the fact that chrysotile fibres tend to fray are very flexible and disintegrate if exposed to acids 12 thus accelerated clearance of inhaled chrysotile fibres from the lungs sounds plausible 13. Inhaled fibers were present in 83 of nonneoplastic lung specimens n 6781 and in 97 of malignant lung specimens n 3233.

Thus of the 114 human lung specimens examined fibers were observed in 99 87. Elastic fibers are absent from scarring keloids and dermatofibromas and they are decreased greatly or are absent in anetodermas. The lung changes in 28 guinea pigs exposed to nylon dust and in 10 exposed to acrylic fibres orlon were studied.

To conduct a mineralogical study on the particles retained in the necropsied lungs of a homogenous group of asbestos miners and millers from asbestos township and a local reference population and to consider the hypothesis that there is a difference in size between fibres retained in the lungs of patients with asbestosis with and without lung cancer. Average length to diameter ratios of the fibres were calculated to be larger in patients with asbestosis and lung cancer than in those without lung cancer for crocidolite fibres or 10 microns long for chrysotile amosite and tremolite fibres 5 to 10 microns long and for chrysotile and crocidolite fibres 5 microns long. The home remedy for fiber glass dust exposure on the skin is to rinse the skin with cold water and applying baby oil.