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The larger features of the tumors are significantly different which helps distinguish between the two.

Lawyers for justice. Localized malignant mesotheliomas are uncommon sharply circumscribed tumors of the serosal membranes with the microscopic appearance of diffuse malignant mesothelioma but without any evidence of diffuse spread. Localized malignant mesotheliomas defined as sharply circumscribed tumors of the serosal membrane with the microscopic appearance of diffuse malignant mesothelioma are rare tumors. Their behavior and prognosis are uncertain.

We report 23 new cases. However because localized mesothelioma is so rare it may be misdiagnosed as another type of cancer. The features at the cellular level are identical for localized and diffuse mesothelioma which can lead to confusion.

We found four such cases in our database. One diffuse mesothelioma stained focally for ber ep4 and electron microscopy confirmed the mesothelial. Intrahepatic mesotheliomas are postulated to arise from mesothelial cells of glissons capsule.

Little is known about their behavior. Rarely however it can present as a localized circumscribed mass or focal pleural lesion without evidence of diffuse spread.

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