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Christina applegate mesothelioma cancer. Desmoplastic malignant pleural mesothelioma dmm is rare histological subtype of diffuse malignant pleural mesothelioma mpm accounting for 5 10 of cases. One study suggest that conventional pleural biopsy is not as good as wedge lung resection at diagnosing desmoplastic mesothelioma. This subtype which accounts for 510 of malignant mesotheliomas most commonly affects the pleura and less commonly the peritoneum and the pericardium24 dmm was first described by kannerstein and churg in 1980 and since then the number of reports although sporadic.
Diagnosing desmoplastic mesothelioma can be tricky. The tissue looks bland and closely resembles benign fibrous tissue. Desmoplastic malignant pleural mesothelioma dmm is rare histological subtype of diffuse malignant pleural mesothelioma mpm accounting for 510 of cases.
Its pathological characteristics include dense collagen fibers in a storiform pattern. In 1980 doctors discovered desmoplastic malignant mesothelioma dmm. For this reason malignant desmoplastic mesothelioma may be misdiagnosed as pleural fibrosis.
Dmm is a subtype of sarcomatoid malignant mesothelioma. Desmoplastic mesothelioma a cell subtype of malignant mesothelioma is a variant of another cell type known as sarcomatoidalthough research is still ongoing in order to find favorable treatment options for this subtype the prognosis is currently grim. Its pathological characteristics include dense collagen fibers in a storiform pattern.
Desmoplastic mesothelioma dmm is a rare and highly lethal variant of malignant pleural mesothelioma. Desmoplastic mesothelioma is a variant of sarcomatoid mesothelioma where desmoplastic refers to the growth of fibrous or connective tissue. Desmoplastic mesothelioma may be misdiagnosed as pleural fibrosis.
We studied 31 patients with fibrotic pleural lesions and classified them as desmoplastic malignant mesothelioma dmm or fibrous pleurisy fp using predetermined histologic criteria including a paucicellular fibrotic pleural lesion with a storiform pattern or the patternless pattern of stout plus 1 or more of the following. Desmoplastic malignant mesothelioma is a cell subtype of mesothelioma cancer. It is thought to account for 5 10 of pleural mesothelioma patients but is often challenging for doctors to diagnose.
It has a poor prognosis with direct invasion of the chest wall or lungs and distant metastases.
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