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Currently desmoplastic mesothelioma is treated with first line chemotherapy a combination of cisplatin and alimta. Desmoplastic mesothelioma is a relatively rare histological subtype of mesothelioma with sarcomatoid histology 1 arising most frequently in the pleura peritoneum or pericardium and less frequently in organs such as lung spleen 4 pancreas 5 and liver 6. Desmoplastic mesothelioma is a rare subtype of malignant mesothelioma and is often difficult to distinguish from reactive pleural fibrosis.

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This subtype which accounts for 510 of malignant mesotheliomas most commonly affects the pleura and less commonly the peritoneum and the pericardium24 dmm was first described by kannerstein and churg in 1980 and since then the number of reports although sporadic.

Lung disease mesothelioma. Neoplasia is the medical term used for both benign and malignant tumors or any abnormal excessive uncoordinated and autonomous cellular or tissue growth. Sarcomatoid refers to long and spindle shaped cells that develop into a rarer and more deadly form of mesothelioma cancer. Recent studies have shown that adding bevacizumab avastin to first line therapy was advantageous for sarcomatoid or mixed histology mesothelioma.

Desmoplastic mesothelioma is a subtype of the sarcomatoid form of mesothelioma. Since its initial report the number of cases of dmm has continued to increase sporadically and it is thought to constitute 510 of all patients with mpm. Is asbestos a culprit.

Desmoplastic malignant pleural mesothelioma dmm is rare histological subtype of diffuse malignant pleural mesothelioma mpm accounting for 5 10 of cases. Turkey is one of the few countries where asbestos related diseases are prevalent. Desmoplastic mesothelioma desmoplastic mesothelioma is a subtype of malignant mesothelioma an incurable cancer typically affecting the tissues that line the lungs heart or abdomen.

Desmoplasia originates from the ancient greek desmos desmos knot bond and plasis plasis formationit is usually used in the description of desmoplastic small round cell tumors. What is desmoplastic mesothelioma. 23 here we describe a patient who lived in a nonendemic area for asbestos related diseases and.

It has a poor prognosis with direct invasion of the chest wall or lungs and distant metastases. Desmoplastic mesothelioma dmm is a rare and highly lethal variant of malignant pleural mesothelioma. Desmoplastic malignant mesothelioma dmm was first described by kannerstein and churg in 1980 and comprises a relatively rare specific histological subtype of sarcomatoid tumor.

In fact few cases of intrapulmonary malignant mesothelioma have been described 2. The presence of dense fibrous tissue with reduced cellular features characterizes the desmoplasia variant of this cancer. Its pathological characteristics include dense collagen fibers in a storiform pattern.

1 it is usually caused by exposure to asbestos either at work or at home. The tumors associated with desmoplastic mesothelioma are usually more than 50 fibrous with a bland hard to recognize pattern.

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This subtype which accounts for 510 of malignant mesotheliomas most commonly affects the pleura and less commonly the peritoneum and the pericardium24 dmm was first described by kannerstein and churg in 1980 and since then the number of reports although sporadic.

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