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Mw law firm. D2 40 is a synthetic antibody for podoplanin. 2 ordonez ng d2 40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma. Not clearly significant breast carcinoma mod pathol 200922216.
Prognostic significance of lymphatic invasion using d2 40 versus he only is unclear. Although immunohistochemistry has proven to be valuable in the differentiation of epithelioid mesothelioma from pulmonary or metastatic adenocarcinoma no single antibody has demonstrated absolute sensitivity or specificity in making this distinction. D2 40 is not a specific marker for cells of mesothelial origin in serous effusions.
D2 40 and podoplanin are highly specific and sensitive immunohistochemical markers of epithelioid malignant mesothelioma. 3 bassarova av nesland jmdavidson b. Using immunohistochemical analysis with d2 40 a.
Differentiate mesothelioma positive even in effusions diagn cytopathol 200735342 from adenocarcinoma negative cancer 2007109933 note. Most mesothelioma cases test positive with d2 40 but other types of cancer sometimes test positive as well. Am j surg pathol 2006.
Podoplanin d2 40 is a mucin type protein that occurs in various types of cells.
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